NIH Director’s Wednesday Afternoon Lecture Series
Dr. Teichmann's group seeks to elucidate general principles of gene expression and protein complex assembly. Her lab is trying to understand how changes in cell state are regulated at the transcriptomic and epigenetic levels by studying the differentiation of mouse T helper (Th) cells and embryonic stem cells (mESC) at the single cell level. Her lab uses and develops both computational and experimental approaches in the field of single cell genomics to address our questions.
Dr. Gahl studies the natural history, diagnosis, and treatment of rare genetic disorders such as cystinosis, Hermansky-Pudlak Syndrome, sialic acid storage diseases, GNE myopathy, and disorders of platelets and pigmentation. He also investigates undiagnosed disorders under the aegis of the NIH Undiagnosed Diseases Program and Network, and pursues new disease discovery.
The major interest of Dr. Hotamisligil's laboratory is to study the regulatory pathways, which control glucose and lipid metabolism. His lab's biochemical and genetic studies focus on signal transduction using cultured mammalian cells as well as transgenic animals to identify specific abnormalities in these pathways, which are involved in human metabolic and inflammatory diseases including obesity, diabetes, fatty liver disease, atherosclerosis, and asthma.
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