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Current Lecture Season

Nonsense-mediated mRNA Decay in Health and Disease

January 9, 2019 - 3:00pm to 4:00pm
Lynne E. Maquat, Ph.D. , University of Rochester School of Medicine and Dentistry

Dr. Maquat is the J. Lowell Orbison Endowed Chair and Professor of Biochemistry and Biophysics in the School of Medicine and Dentistry, Director of the Center for RNA Biology, and Chair of Graduate Women in Science at the University of Rochester, Rochester, NY. After obtaining her Ph.D. in Biochemistry from the University of Wisconsin-Madison and undertaking post-doctoral work at the McArdle Laboratory for Cancer Research, she joined Roswell Park Cancer Institute before moving to the University of Rochester.

The social life of DNA

January 16, 2019 - 3:00pm to 4:00pm
Alondra Nelson, Ph.D., M.Phil., Columbia University

Dr. Nelson is president of the Social Science Research Council and professor of sociology at Columbia University. An award-winning scholar of science, medicine, and social inequality, her recent books include The Social Life of DNA: Race, Reparations, and Reconciliation after the GenomeGenetics and the Unsettled Past: The Collision of DNA, Race, and History, and Body and Soul: The Black Panther Party and the Fight Against Medical Discrimination. Dr.

Molecular engineering of immunotherapeutics: from regulation in autoimmunity to immunity to cancer

January 23, 2019 - 3:00pm to 4:00pm
Jeffrey A. Hubbell, Ph.D. , University of Chicago Institute for Molecular Engineering

Dr. Hubbell uses biomaterials and protein engineering approaches to investigate topics in regenerative medicine and immunotherapeutics. In regenerative medicine, he focuses on biomaterial matrices that mimic the extracellular matrix and on growth factor - extracellular matrix interactions, working in a variety of animal models of regenerative medicine.

What the fly brain can teach us about the neural mechanisms of complex behaviors

January 30, 2019 - 3:00pm to 4:00pm
Gerald M. Rubin, Ph.D. , Howard Hughes Medical Institute

Dr. Rubin will discuss the current state of circuit neuroscience in the fly, using examples from his lab’s work on learning and memory, sleep and aggression. Within the next five years, those of us working with Drosophila can expect to have comprehensive datasets, including a complete connectome, and powerful tools with which to study the fly’s brain and behavior.

Microbial networking (…it’s like Tinder for bugs)

February 6, 2019 - 3:00pm to 4:00pm
Elodie Ghedin, Ph.D. , New York University

Research in the Ghedin Lab meets at the interface of microbiology, genomics, and systems biology. Projects touch on the extent of intra- and inter-host microparasite (viruses and bacteria) diversity within the context of transmission and virulence, and parse the relationship between microbial ecology in the respiratory tract and disease progression.

Cancer and aging: rival demons?

February 13, 2019 - 3:00pm to 4:00pm
Judith Campisi, Ph.D. , Buck Institute for Research on Aging

Cancer and aging are intricately intertwined. Organisms with dividing cells are at a substantial risk for developing cancer. Evolution “solved” the cancer problem by selecting for tumor suppressive mechanisms, which protect these organisms for cancer – at least for the reproductively active portion of the life span. Beyond that portion of the life span, these mechanisms can drive pathologies associated with aging, including, ironically, cancer. For her lecture, Dr.

Pediatric immune diseases, all genetics?

February 20, 2019 - 3:00pm to 4:00pm
Alain Fischer, M.D., Ph.D. , Institut Imagine/Collège de France

Dr. Fischer is interested in understanding how genetic errors cause vulnerability to microorganisms, autoimmunity, inflammation and allergy, with the dual goal to decipher in vivo immunity in humans and to correct its defects.

Autoantigens and autoimmunity: a bedside to bench and back again story

February 27, 2019 - 3:00pm to 4:00pm
Sandra L. Wolin, M.D., Ph.D., National Cancer Institute

Noncoding RNAs play critical roles in the metabolism of all cells. The Wolin laboratory studies how noncoding RNAs function, how cells recognize and degrade defective noncoding RNAs, and how failure to degrade these RNAs affects cell function and contributes to human disease. Their studies revealed new mechanisms by which defective RNAs are targeted for degradation and new classes of noncoding RNAs. Most recently, their work has contributed to a novel theory for how the autoimmune disease systemic lupus erythematosus may be triggered in genetically susceptible individuals.

The opioid crisis: how can we bridge the vast gap between science and practice? 

March 6, 2019 - 3:00pm to 4:00pm
Sharon Walsh, Ph.D. , University of Kentucky

Dr. Walsh's clinical research has focused on pharmacological issues in opioid and cocaine dependence. She has conducted studies on pharmacodynamic and pharmacokinetic characteristics of opioid treatment agents, including buprenorphine, methadone and LAAM and has evaluated potential pharmacotherapies for efficacy and safety in the treatment of cocaine dependence. 

How to bust up a bacterial biofilm

March 27, 2019 - 3:00pm to 4:00pm
Lauren O. Bakaletz, Ph.D. , The Research Institute at Nationwide Children’s Hospital

The Bakaletz laboratory’s research focus is attempting to understand the pathogenic mechanisms operational in the highly prevalent pediatric disease, otitis media (OM) (or middle ear infection). Specifically, we are interested in elucidating how upper respiratory tract viruses predispose the middle ear to invasion by any of the three predominant bacterial pathogens of OM (nontypeable Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae).

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The page was last updated on Wednesday, June 11, 2014 - 4:07pm