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NIH Director’s Wednesday Afternoon Lecture Series


Accepting nominations for the 2022–2023 WALS season through January 21, 2022.

Watch lectures live at at the time of the event.
Binge-watch the archives dating back more than 20 years at

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Upcoming Lectures

Advancing Therapies for Neurofibromatosis Type 1 (NF1): Lessons Learned from Every Patient

December 8, 2021 - 3:00pm to 4:00pm
Brigitte Widemann, M.D., National Institutes of Health, National Cancer Institute

Dr. Brigitte Widemann is a pediatric oncologist with the primary interest of developing effective therapies for children and adults with genetic tumor predisposition syndromes, such as neurofibromatosis type 1 (NF1), and rare solid tumors through innovative clinical trial design. Dr. Widemann currently serves as the head of the Pharmacology & Experimental Therapeutics Section and as Chief of NCI’s Pediatric Oncology Branch. Anticancer drug discovery and development are moving towards a more rational and targeted approach.

Cytokine Signaling: The More Things Change, the More They Stay the Same

December 15, 2021 - 3:00pm to 4:00pm
John O'Shea, M.D., National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH

Cytokines are critical for host defense but are also key factors in immune and inflammatory diseases. Innate and adaptive lymphocytes, including T cells, are important selective producers of cytokines, and it is through the production of these that immune responses work together to eliminate microbial pathogens. Host defense against pathogenic microorganisms requires this elegant means of communication between innate and adaptive arms of the immune system.

TBA, on biological networks

January 5, 2022 - 3:00pm to 4:00pm
Danielle Bassett, Ph.D., University of Pennsylvania

The page was last updated on Tuesday, December 7, 2021 - 10:30am