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Knowing Right From Wrong (Protein Conformation): The Challenging Choices of (Molecular) Chaperones

Wednesday, March 16, 2022 - 3:00pm to 4:00pm

Speaker

Judith Frydman, Ph.D.
Donald Kennedy Chair, School of Humanities and Sciences
Professor of Genetics
Stanford Medicine

Summary

The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.


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